Steroids in the Prophylaxis of Fat Embolism Syndrome

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The fat embolism syndrome.

The fat embolism syndrome, often a complication of major trauma, frequently passes undiagnosed. The classical picture of cerebral confusion, respiratory distress and petechiae of skin and mucosa is not always seen. A distinction must be made between the clinical entity and fat embolism demonstrated pathologically. Post-mortem, fat embolism is often found after deaths from causes other than trau...

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Efficacy of Corticosteroids in Prevention of Fat Embolism Syndrome in Patients with Long Bone Fracture

Fat embolism syndrome refers to a constellation of symptoms secondary to the presence of fat globules in the lung parenchyma and/or peripheral blood circulation. The syndrome is most often seen in association with long bone or pelvic fractures and can cause significant morbidity and mortality. The present randomized double blind placebo-controlled trial was conducted to evaluate the efficacy of...

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Is There Any Role of Inhalational Corticosteroids in the Prophylaxis of Post-Traumatic Fat Embolism Syndrome?

Fat embolism syndrome (FES) is primarily a lung parenchymal disorder resulting from interstitial and alveolar inflammation triggered by the lipid metabolites in blood circulation. The 'low-dose' corticosteroid is supposed to have a prophylactic effect on the incidence of the FES and arterial hypoxemia by reducing this inflammatory response. It is expected that inhaled corticosteroids (ciclesoni...

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Fat Embolism Syndrome

The initial symptoms are probably caused by mechanical occlusion of multiple blood vessels with fat globules that are too large to pass through the capillaries. The vascular occlusion in fat embolism is often temporary or incomplete, as fat globules do not obstruct capillary blood flow completely because of their fluidity and deformability. The late presentation is thought to be a result of hyd...

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ژورنال

عنوان ژورنال: Journal of Aquaculture Research & Development

سال: 2012

ISSN: 2155-9546

DOI: 10.4172/scientificreports.381